abstract：:The concept of neural plasticity and the early natural abilities of hearing children to acquire speech and language without instruction have led many authorities to advocate cochlear implantation before the age of 5 years in congenital deafness. Older children therefore become lower priority for scarce public funds be...

journal_title：Archives of disease in childhood

authors： Gray RF,Jones SE,Court I

更新日期：2003-08-01 00:00:00

abstract：:This review focuses on recent advances of topical interest regarding the diagnosis and treatment of common causes of bacterial meningitis occurring in children beyond the neonatal period. Tuberculous meningitis is beyond the scope of this review. ...

journal_title：Archives of disease in childhood

authors： El Bashir H,Laundy M,Booy R

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:The Coventry Consensus in 1998 recommended a single height measurement of all children at school entry or around the age of 5 years and prompt referral of children with height <0.4th centile for further assessment, in order to identify undetected and treatable asymptomatic growth disorders. AIM:To determine...

journal_title：Archives of disease in childhood

authors： Banerjee S,Morgan RJ,Rees SA,Latif AH

更新日期：2003-06-01 00:00:00

abstract：AIMS:To investigate a population of individuals with 22q11 deletion syndrome for hypocalcaemia. METHODS:A detailed clinical history enquiring into symptoms of hypocalcaemia and blood sampling to assess for hypocalcaemia and hypoparathyroidism, of patients outside the neonatal period known to have the 22q11 microdeleti...

journal_title：Archives of disease in childhood

authors： Taylor SC,Morris G,Wilson D,Davies SJ,Gregory JW

更新日期：2003-06-01 00:00:00

abstract：:Linkage of bacterial capsular polysaccharides to proteins to create conjugate vaccines has had a dramatic impact on the health of children. Although unconjugated polysaccharides are poorly immunogenic in infants and some older children and adults, their covalent coupling with proteins stimulates T cell dependent antig...

journal_title：Archives of disease in childhood

authors： Baker CJ,Edwards MS

更新日期：2003-05-01 00:00:00

abstract：:In a cohort of 14 children with identical cardiac xenografts, two boys developed acute myeloid leukaemia 11 and 16 months respectively after the operation. A dedicated working group designed a scheme intending to take care of all aspects of the situation. This article focuses on preferred strategies towards patients, ...

journal_title：Archives of disease in childhood

authors： Ruud E,Thaulow E,Früh A,Lindberg H,Lie SO

更新日期：2003-05-01 00:00:00

abstract：:We report a child with Down's syndrome in whom metrorrhagia and precocious puberty revealed primary autoimmune hypothyroidism. The patient had a decreased growth velocity, exaggerated weight gain, bone age delay, and bilaterally enlarged multicystic ovaries. Delays in the diagnosis and treatment of hypothyroidism can ...

journal_title：Archives of disease in childhood

authors： Chemaitilly W,Thalassinos C,Emond S,Thibaud E

更新日期：2003-04-01 00:00:00

abstract：:Syncope in childhood is very common. The vast majority of episodes are benign, and are due to neurocardiogenic syncope. Only a minority are due to something potentially more serious or life threatening. The diagnosis and differentiation of benign from more serious causes of syncope is made primarily by the history. In...

journal_title：Archives of disease in childhood

authors： McLeod KA

更新日期：2003-04-01 00:00:00

abstract：AIMS:To ascertain whether the reduction in nasopharyngeal carriage of vaccine serotypes induced by pneumococcal conjugate vaccine (PnCV) administered to infants persists beyond the age of 2 years. METHODS:Non-randomised, unblinded controlled study of 2-5 year old children who had received three doses of heptavalent Pn...

journal_title：Archives of disease in childhood

authors： Lakshman R,Murdoch C,Race G,Burkinshaw R,Shaw L,Finn A

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Previous research has indicated that children who have received treatment for leukaemia which includes cranial irradiation exhibit deficits in their ability to focus attention. It has been suggested that the use of cranial irradiation may have a role to play in long term sequelae. AIMS:To investigate neurop...

journal_title：Archives of disease in childhood

authors： Rodgers J,Marckus R,Kearns P,Windebank K

更新日期：2003-02-01 00:00:00

abstract：:Cerebral oedema is the most common cause of mortality and morbidity during the first day of conventional treatment for diabetic ketoacidosis in paediatric patients. It is possible that therapy contributes to its development. Risk factors that predispose to cerebral oedema should lead to an expansion of the intracellul...

journal_title：Archives of disease in childhood

authors： Carlotti AP,Bohn D,Halperin ML

更新日期：2003-02-01 00:00:00

abstract：:Life was sorted. With membership of the college under my belt, and my paediatric training completed, I needed a new challenge. I decided to launch into the deep waters of qualitative research. Stepping out with some trepidation into semistructured interviews and grounded theory, I soon found that the water was neither...

journal_title：Archives of disease in childhood

authors： Sidebotham P

更新日期：2003-01-01 00:00:00

abstract：:The allergic response is distinct from other immune reactions in its reliance on IgE, its high affinity receptor, Fc epsilon RI, and the primary effector cell--the tissue mast cell. Positive skin tests or raised concentrations of specific immunoglobulin E (IgE) in the serum define IgE sensitisation or "atopy". IgE par...

journal_title：Archives of disease in childhood

authors： Milgrom H

更新日期：2003-01-01 00:00:00

abstract：AIMS:To evaluate behavioural outcome and quality of life in children aged 8-14 years after neonatal arterial switch operation for transposition of the great arteries. METHODS:Sixty children operated as neonates with combined deep hypothermic circulatory arrest and low flow cardiopulmonary bypass were evaluated at age ...

journal_title：Archives of disease in childhood

authors： Hövels-Gürich HH,Konrad K,Wiesner M,Minkenberg R,Herpertz-Dahlmann B,Messmer BJ,Von Bernuth G

更新日期：2002-12-01 00:00:00

abstract：:"Mental retardation" is a modern term for an age old problem. The descriptions of paediatric cases contained within the works of Thomas Willis (1621-75) have been increasingly recognised for their insight into seventeenth century child health practices. ...

journal_title：Archives of disease in childhood

authors： Williams AN

更新日期：2002-12-01 00:00:00

abstract：AIMS:To assess the impact of two paediatric intensive care unit retrieval teams on the performance of three mortality risk scoring systems: pre-ICU PRISM, PIM, and PRISM II. METHODS:A total of 928 critically ill children retrieved for intensive care from district general hospitals in the south east of England (crude m...

journal_title：Archives of disease in childhood

authors： Tibby SM,Taylor D,Festa M,Hanna S,Hatherill M,Jones G,Habibi P,Durward A,Murdoch IA

更新日期：2002-11-01 00:00:00

abstract：:Nerve growth factor (NGF) is the first described neurotrophin that stimulates the growth and differentiation of nerve cells and promotes skin and peripheral tissue regeneration. Recent studies suggest that NGF influences endothelial cell proliferation and angiogenic activity. In view of these proposed regenerative eff...

journal_title：Archives of disease in childhood

authors： Chiaretti A,Piastra M,Caresta E,Nanni L,Aloe L

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Heart murmurs are common in children, and they are often referred to a specialist for examination. A clinically innocent murmur does not need further investigation. The referral area of the University Hospital is large and sparsely populated. A new service for remote auscultation (telemedicine) of heart murm...

journal_title：Archives of disease in childhood

authors： Dahl LB,Hasvold P,Arild E,Hasvold T

更新日期：2002-10-01 00:00:00

abstract：AIMS:(1) To determine the pattern of respiratory impairment in children with thalassaemia major (TM); (2) to assess the relation between the degree of respiratory impairment and total body iron content. METHODS:Twenty nine TM patients were recruited. All underwent physical examination, standardised pulmonary function ...

journal_title：Archives of disease in childhood

authors： Li AM,Chan D,Li CK,Wong E,Chan YL,Fok TF

更新日期：2002-10-01 00:00:00

abstract：:Concerns have been raised about the hazards of the insulin tolerance test (ITT), used to measure growth hormone secretion. In Glasgow, we continue to use this test, adhering to a strict protocol. A review of outcome over a 10 year period (1989-99), during which 550 ITTs were performed, was undertaken. No serious adver...

journal_title：Archives of disease in childhood

authors： Galloway PJ,McNeill E,Paterson WF,Donaldson MD

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Long term growth hormone (GH) treatment in children with idiopathic short stature (ISS) results in a relatively small mean gain in final height of 3-9 cm, which may not justify the cost of treatment. As it is unknown whether GH treatment during puberty adds to final height gain, we sought to improve the cost...

journal_title：Archives of disease in childhood

authors： Kamp GA,Waelkens JJ,de Muinck Keizer-Schrama SM,Delemarre-Van de Waal HA,Verhoeven-Wind L,Zwinderman AH,Wit JM

更新日期：2002-09-01 00:00:00

abstract：AIMS:To compare the effectiveness of short course (2-4 days) with standard duration oral antibiotic treatment (7-14 days) for urinary tract infection (UTI). METHODS:Meta-analysis of randomised controlled trials using a random effects model. Ten trials were eligible, involving 652 children with lower tract UTI recruite...

journal_title：Archives of disease in childhood

authors： Michael M,Hodson EM,Craig JC,Martin S,Moyer VA

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Most children with daytime wetting have detrusor instability. A minority have neuropathic vesicourethral dysfunction. The commonest cause is spina bifida, which may be closed. Clinical features suggestive of closed spina bifida include cutaneous, neuro-orthopaedic or lumbosacral spine x ray abnormalities, im...

journal_title：Archives of disease in childhood

authors： Wraige E,Borzyskowski M

更新日期：2002-08-01 00:00:00

abstract：AIMS:To assess the efficacy of a new regimen of intravenous atropine treatment for infantile hypertrophic pyloric stenosis (IHPS) with special reference to regression of pyloric hypertrophy. METHODS:Atropine was given intravenously at a dose of 0.01 mg/kg six times a day before feeding in 19 patients with IHPS diagnos...

journal_title：Archives of disease in childhood

authors： Kawahara H,Imura K,Nishikawa M,Yagi M,Kubota A

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:There are few data on the optimal micronutrient composition of paediatric enteral feeds. The recent European Directive on Foods for Special Medical Purposes (1999/21/EC) did not distinguish between the composition of adult and paediatric feeds. AIMS:To evaluate, in an open, observational study, the long ter...

journal_title：Archives of disease in childhood

authors： Johnson TE,Janes SJ,MacDonald A,Elia M,Booth IW

更新日期：2002-06-01 00:00:00

abstract：:Idiopathic pulmonary haemosiderosis is a very rare but devastating disorder. Diagnosis is sometimes difficult and the clinical course exceedingly variable, as illustrated by this report of a girl, aged 2 years 4 months, with severe iron deficiency anaemia. There was no response to iron therapy and transfusions. Sustai...

journal_title：Archives of disease in childhood

authors： Yao TC,Hung IJ,Jaing TH,Yang CP

更新日期：2002-06-01 00:00:00

abstract：AIMS:To assess sickle cell pain and coping in children and to examine the relation between these factors and the utilisation of health services. METHODS:Cross sectional study involving 67 children with sickle cell disease attending three London hospitals. Interviews and questionnaires involved measures of pain, health...

journal_title：Archives of disease in childhood

authors： Anie KA,Steptoe A,Ball S,Dick M,Smalling BM

更新日期：2002-05-01 00:00:00

abstract：AIMS:To document the patterns of presentation and outcome of severe anticholinesterase insecticide poisoning in children requiring intensive care. METHODS:Retrospective case note review of all 5541 children admitted to the paediatric intensive care unit (PICU) of a university hospital during the 10 years from January ...

journal_title：Archives of disease in childhood

authors： Verhulst L,Waggie Z,Hatherill M,Reynolds L,Argent A

更新日期：2002-05-01 00:00:00

abstract：AIMS:To determine the prevalence of petechial spots in well babies. METHODS:A total of 116 babies under the age of 12 months were fully examined at child health surveillance clinics. The number and site of petechiae were recorded together with details of possible causes. RESULTS:A total of 27.6% of babies had one or ...

journal_title：Archives of disease in childhood

authors： Downes AJ,Crossland DS,Mellon AF

更新日期：2002-04-01 00:00:00

abstract：AIMS:To obtain information about the health and well being of 108 boys six years after their involvement with the same paedophile. METHODS:Case-control study of the health records of 93 male victims of a major episode of school based child sexual abuse and 93 matched controls. Interviews with a sample of their general...

journal_title：Archives of disease in childhood

authors： Price L,Maddocks A,Davies S,Griffiths L

更新日期：2002-03-01 00:00:00

abstract：AIMS:To evaluate the performance of the Paediatric Risk of Mortality (PRISM) score in a population of UK children and to use this score to examine severity of illness adjusted mortality of critically ill children <16 years old in a defined geographical region. METHODS:Observational study of a defined population of cri...

journal_title：Archives of disease in childhood

authors： Henderson AJ,Garland L,Warne S,Bailey L,Weir P,Edees S

更新日期：2002-03-01 00:00:00

abstract：:Post-thrombotic syndrome (PTS) is a potentially disabling complication occurring in up to 67% of adult patients following deep venous thrombosis (DVT). PTS has recently been recognised in children. We present three cases of symptomatic PTS in children, which occurred following the use of central venous lines (CVLs). I...

journal_title：Archives of disease in childhood

authors： Barnes C,Newall F,Monagle P

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Studies have shown a correlation between increased accident rates and levels of deprivation in the community. School accident reporting is one area where an association might be expected. AIMS:To investigate differences in primary school accident rates in deprived and more affluent wards, in an area managed...

journal_title：Archives of disease in childhood

authors： Latif AH,Williams WR,Sibert J

更新日期：2002-02-01 00:00:00

abstract：:A child showing signs of Henoch-Schönlein purpura developed a right tibiofibular vascular thrombosis. Antiphospholipid antibody tests were positive for both lupus anticoagulant and anticardiolipin antibodies. This suggests that an antiphospholipid syndrome should be considered in cases of Henoch-Schönlein purpura and ...

journal_title：Archives of disease in childhood

authors： Monastiri K,Selmi H,Tabarki B,Yacoub M,Mahjoub T,Essoussi AS

更新日期：2002-02-01 00:00:00

abstract：AIMS:To establish whether subjects with previous evidence of sleep apnoea prior to adenotonsillectomy continue to have evidence of narrower upper airways during sleep, 12 years later. METHODS:Twenty subjects (median age 16 years) underwent repeat sleep studies at home, 12 years after such studies had shown significant...

journal_title：Archives of disease in childhood

authors： Tasker C,Crosby JH,Stradling JR

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The case fatality rate from meningococcal disease (MD) has remained relatively unchanged in the post antibiotic era, with 20-50% of patients who develop shock still dying. In 1992 a new paediatric intensive care unit (PICU) specialising in MD was opened. Educational information was disseminated to l...

journal_title：Archives of disease in childhood

authors： Booy R,Habibi P,Nadel S,de Munter C,Britto J,Morrison A,Levin M,Meningococcal Research Group.

更新日期：2001-11-01 00:00:00

abstract：AIMS:To review the precipitating events, clinical features, treatment, and outcome of macrophage activation syndrome (MAS). METHODS:Retrospective review of cases of MAS from a prospectively collected database of children with rheumatic diseases from 1980 to 2000. RESULTS:Nine patients (eight girls) were considered to...

journal_title：Archives of disease in childhood

authors： Sawhney S,Woo P,Murray KJ

更新日期：2001-11-01 00:00:00

abstract：:Lung function measurements with and without a disposable bacterial filter were compared in 60 children. Although statistically significant, the reduction of lung function measurements caused by using bacterial filters was small and clinically irrelevant (2-4% of predicted for forced expiratory volume in one second and...

journal_title：Archives of disease in childhood

authors： Kamps AW,Vermeer K,Roorda RJ,Brand PL

更新日期：2001-10-01 00:00:00

abstract：:Cholelithiasis is considered uncommon in infancy, childhood, and adolescence. We performed a prospective, controlled study showing that children with Down's syndrome have a significantly higher prevalence of cholelithiasis (4.7%) compared with controls (0.2%). Clinicians should be aware of the risk of gallstones in ch...

journal_title：Archives of disease in childhood

authors： Toscano E,Trivellini V,Andria G

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:To examine whether behavioural or cognitive sequelae of otitis media with effusion (OME) continue into late childhood and the early teens (11-18 years). SETTING:Data from a large multipurpose birth cohort study: the Dunedin multidisciplinary health and development study. PARTICIPANTS:Around 1000 children fr...

journal_title：Archives of disease in childhood

authors： Bennett KE,Haggard MP,Silva PA,Stewart IA

更新日期：2001-08-01 00:00:00